Molecular Diagnostics

Genvinset® HLA CELIAC Plus is an in vitro diagnostic kit for the detection of HLA-DQB1*02, DQB1*03:02, DQA1*05 and DQA1*03 alleles in genomic DNA extracted from whole blood, and the consequent determination of DQ2 and DQ8 antigens associated to celiac disease. The kit is able to determine the homozygosity or heterozygosity status for the DQB1*02 alleles. The analysis is based on real-time PCR technology using TaqMan® probes.

Genvinset® HLA B57v5 is an in vitro diagnostic kit for the determination of the HLA-B*57:01 allele in genomic DNA extracted from whole blood, associated with abacavir hypersensitivity reaction, by real-time PCR using Taqman® probes technology.

Genvinset® PAI-1 4G/5G is a kit for the in vitro qualitative detection of the 4G/5G deletion (NCBI dbSNP rs1799762; NM_000602.5:c.-820G[(4_5)]) in the promoter region of the Plasminogen activator inhibitor 1 (SERPINE1) gene (OMIM: 173360) associated with thrombophilia risk, in genomic DNA extracted from whole blood using Real Time PCR technology with specific TaqMan® probes.

Genvinset® HLA DQA1*05 is a semi-automated in vitro diagnostic kit for the qualitative detection of the HLA-DQA1*05 allele in genomic DNA extracted from whole blood, associated with the immunogenicity of anti-TNF drugs, by Real-Time PCR using TaqMan® probes technology.

Kit for detecting HLA-DRB1*03, DRB1*04, DQB1*02:01 and DQB1*03:02 alleles by Real Time PCR using TaqMan® probes technology.

Kit for detecting the HLA-C*06 alleles by Real Time PCR using TaqMan® probes technology.

Kit for the determination of the CAG and CTA/CTG triplet repeats number (SCAs 1, 2, 3, 6, 7 and SCA 8, respectively) by fluorescent fragment analysis.

BactoReal® Kit A. baumannii & P. mirabilis ist ein nicht automatischer in-vitro Diagnostik Test zum qualitativen Nachweis und Identifizierung der extrahierten DNA von Acinetobacter baumannii (rpoB Gen) und Proteus mirabilis (ureC Gen) aus humanem EDTA-Blut, Punktaten und Liquor mittels real-time Polymerase-Kettenreaktion