Vinculin antibody
In stock
SKU/Catalog Number
PAab09800
Catalog Number: PAab09800
- Isotype IgG1.
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.).
- Background/ FUNCTION.
- Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament(F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It may also play important roles in cell morphology and locomotion. Vinculin is a 117-kDa, 1,066-amino-acid protein which is ubiquitously expressed. Its splice variant, metavinculin(124 kDa), is muscle-specific.
- Immunogen vinculin.
- Specificity Human, Rat, Mouse.
- Tested Application ELISA, FC, IF, IHC, WB.
- Recommended dilution WB: 1:2000-1:20000; IHC: 1:50-1:500; IF: 1:50-1:500.
- IHC use Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using PAab09800(Vinculin Antibody) at dilution of 1:200.
- WB use.
- hela lysates were subjected to SDS PAGE followed by western blot with PAab09800(Vinculin Antibody) at dilution of 1:5000.
- Protein Information.
- Gene ID.
- Uniprot ID P18206.
- Calculated MW 124 kDa.
- Research Area Immunology, Cardiovascular.
- Alternative Name CMD1W, Metavinculin, MVCL, VCL, Vinculin.
| Intended Use | Purification Protein A+G purification , Purity 95% as determined by SDS-PAGE. |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab09800 |
| Manufacturer | Life Science Market |
| Certification | For research only |
| Order | Request Quote |
