Vinculin antibody

In stock
SKU/Catalog Number
PAab09799

Catalog Number: PAab09799

  • Isotype IgG.
  • Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.).
  • Background/ FUNCTION.
  • Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
  • Immunogen vinculin
  • . Specificity Human, Mouse, Rat.
  • Tested Application ELISA, IHC, WB.
  • Recommended dilution WB: 1:500-1:2000; IHC: 1:50-1:200.
  • IHC use Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using PAab09799( Vinculin Antibody) at dilution of 1:100.
  • WB use.
  • HepG2 cells were subjected to SDS PAGE followed by western blot with PAab09799(Vinculin Antibody) at dilution of 1:1000.
  • Protein Information.
  • Gene ID 7414.
  • Uniprot ID P18206.
  • Calculated MW 124 kDa.
  • Research Area Immunology, Cardiovascular.
  • Alternative Name CMD1W, Metavinculin, MVCL, VCL, Vinculin.
More Information
Intended UsePurification Immunogen affinity purified , Purity 95% as determined by SDS-PAGE.
Companybioactiva diagnostica GmbH
Storage condition2-8°C
Product NumberPAab09799
ManufacturerLife Science Market
CertificationFor research only
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