TNF alpha antibody
In stock
SKU/Catalog Number
PAab09822
Catalog Number: PAab09822
- Isotype IgG.
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.).
- Background/ FUNCTION.
- This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
- Immunogen tumor necrosis factor (TNF superfamily, member 2).
- Specificity Human, Mouse, Rat.
- Tested Application ELISA, WB, IHC.
- Recommended dilution WB: 1:1000 - 1:2000; IHC: 1:50 - 1:100.
- IHC use Immunohistochemistry of paraffin-embedded human stomach tissue slide using PAab09822( TNF-a Antibody) at dilution of 1:100.
- WB use Hela cells were subjected to SDS PAGE followed by western blot with PAab09822( TNF-a Antibody) at dilution of 1:1000.
- Protein Information.
- Gene ID 7124.
- Uniprot ID P01375.
- Calculated MW 21 kDa.
- Research Area Signal Transduction, Cardiovascular, Cancer, Immunology, Neuroscience.
- Alternative Name Cachectin, DIF, TNF, TNF a, TNF alpha, TNFA, TNF-a, TNFSF2, Tumor necrosis factor.
| Intended Use | Purification Immunogen affinity purified , Purity 95% as determined by SDS-PAGE. |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab09822 |
| Manufacturer | Life Science Market |
| Certification | For research only |
| Order | Request Quote |
