TLR4 antibody
In stock
SKU/Catalog Number
PAab09837
Catalog Number: PAab09837
- Isotype IgG2b.
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.).
- Background/ FUNCTION.
- TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
- Immunogen toll-like receptor 4.
- Specificity Human, Mouse, Rat.
- Tested Application ELISA, WB, IHC.
- Recommended dilution WB: 1:1000-1:8000; IHC: 1:50-1:500.
- IHC use Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using PAab09837( TLR4 Antibody) at dilution of 1:200.
- WB use RAW 264.7 cells were subjected to SDS PAGE followed by western blot with PAab09837( TLR4 Antibody) at dilution of 1:4000.
- Protein Information.
- Gene ID 7099.
- Uniprot ID O00206.
- Calculated MW 35 kDa.
- Research Area Neuroscience, Immunology, Signal Transduction, Developmental biology.
- Alternative Name ARMD10, CD284, hToll, TLR4, TOLL, toll like receptor 4.
| Intended Use | Purification Protein A+G purification , Purity 95% as determined by SDS-PAGE. |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab09837 |
| Manufacturer | Life Science Market |
| Certification | For research only |
| Order | Request Quote |
