SOCS1 antibody
In stock
SKU/Catalog Number
PAab09926
Catalog Number: PAab09926
- Isotype IgG.
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.).
- Background/ FUNCTION.
- This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
- Immunogen Suppressor of cytokine signaling 1.
- Specificity Human, Mouse, Rat.
- Tested Application ELISA, WB.
- Recommended dilution WB: 1:500 - 1:2000.
- IHC use.
- WB use.
- mouse lung were subjected to SDS PAGE followed by western blot with PAab09926 (SOCS1 antibody) at dilution of 1:1000.
- Protein Information.
- Gene ID 8651.
- Uniprot ID O15524.
- Calculated MW 24 kDa.
- Research Area Metabolism, Signal Transduction.
- Alternative Name CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3.
| Intended Use | Purification Immunogen affinity purified , Purity 95% as determined by SDS-PAGE. |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab09926 |
| Manufacturer | Life Science Market |
| Certification | For research only |
| Order | Request Quote |
