SMARCA4 antibody
In stock
SKU/Catalog Number
PAab10044
Catalog Number: PAab10044
- Isotype IgG.
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.).
- Background/ FUNCTION.
- SMARCA4, also named as BAF190A, BRG1, SNF2B and SNF2L4, belongs to the SNF2/RAD54 helicase family. SMARCA4 is a transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. It is a component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. It is also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor(VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.
- Immunogen SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4.
- Specificity Human, Mouse.
- Tested Application ELISA, WB, IHC.
- Recommended dilution WB: 1:500 - 1:2000; IHC: 1:50 - 1:200.
- IHC use Immunohistochemistry of paraffin-embedded human lung cancer using PAab10044(SMARCA4 antibody) at dilution of 1:100.
- WB use.
- HeLa cells were subjected to SDS PAGE followed by western blot with PAab10044(SMARCA4 antibody) at dilution of 1:1000.
- Protein Information.
- Gene ID 6597.
- Uniprot ID P51532.
- Calculated MW 185 kDa.
- Research Area Epigenetics, Stem Cells, Metabolism.
- Alternative Name ATP dependent helicase SMARCA4, BAF190, BAF190A, BRG1, BRG1 associated factor 190A, FLJ39786, hSNF2b, Protein brahma homolog 1, Protein BRG 1, SMARCA4, SNF2, SNF2 BETA, SNF2B, SNF2L4, SNF2LB, SWI2, Transcription activator BRG1.
| Intended Use | Purification Immunogen affinity purified , Purity 95% as determined by SDS-PAGE. |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab10044 |
| Manufacturer | Life Science Market |
| Certification | For research only |
| Order | Request Quote |
