PTCH1 antibody
In stock
SKU/Catalog Number
PAab10084
Catalog Number: PAab10084
- Isotype IgG.
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.).
- Background/ FUNCTION.
- Acts as a receptor for sonic hedgehog(SHH), indian hedgehog(IHH) and desert hedgehog(DHH). Associates with the smoothened protein(SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
- Immunogen patched homolog 1.
- Specificity Human, Rat.
- Tested Application ELISA, IHC.
- Recommended dilution IHC: 1:20-1:200.
- IHC use Immunohistochemistry of paraffin-embedded human colon cancer using PAab10084(PTCH1 antibody) at dilution of 1:50.
- WB use.
- Protein Information.
- Gene ID 5727.
- Uniprot ID Q13635.
- Calculated MW 161 kDa.
- Research Area Neuroscience, Cell Division and Proliferation.
- Alternative Name HPE7, NBCCS, Patched, patched homolog 1, Patched1, Protein patched homolog 1, PTC, PTC1, PTCH, PTCH1, PTCH11.
| Intended Use | Purification Immunogen affinity purified , Purity 95% as determined by SDS-PAGE. |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab10084 |
| Manufacturer | Life Science Market |
| Certification | For research only |
| Order | Request Quote |
