Molecular Diagnostics is the application of molecular biology techniques to study human diseases, using core molecular biology methods such as nucleic acid isolation/quantification, ELISA assays, ... Read More
Molecular Diagnostics is the application of molecular biology techniques to study human diseases, using core molecular biology methods such as nucleic acid isolation/quantification, ELISA assays, in situ hybridization, PCR amplification, and mass spectrometry, among others.Molecular Diagnostic-based tests from Bioactiva catalogcan provide specific information required to identify a range of clinical conditions in infectious diseases, genetic screenings, oncological disorders, and provide help in guiding therapies of specific targets.
For example, Real-time Polymerase Chain Reaction (PCR) kits available at Bioactiva allow for an early and highly specificdiagnosis, thus leading to a fast and selective treatment of the individual patient. Also, Enzyme-Linked Immunosorbent Assays (ELISA) can quantify antibodies, antigens, proteins or glycoproteins in different types of biological probes, human or animal.
Molecular diagnostic kits from Bioactiva are based on the latest research and are performed on the most sophisticated platforms available to the clinical laboratory. Monitoring gene activity with molecular diagnostic assays empowers laboratories to better inform clinical decisions.
Genvinset® HLA DQA1*05 is a semi-automated in vitro diagnostic kit for the qualitative detection of the
HLA-DQA1*05 allele in genomic DNA extracted from whole blood, associated with the immunogenicity of
anti-TNF drugs, by Real-Time PCR using TaqMan® probes technology.
Genvinset® Lactose Intolerance is a semi-automated in vitro diagnostic kit for the qualitative detection of the polymorphisms -13910 C/T (NCBI dbSNP rs4988235; NM_005915.6: c.1917+326C>T) and -22018 G/A (NCBI dbSNP rs182549; NM_005915.5: c.1362+117G>A) of the MCM6 gene (OMIM: 601806) associated with lactase persistence, in genomic DNA extracted from whole blood, by Real Time PCR using specific TaqMan® probes technology.
Adellgene Fragile X Screening is a diagnostic kit designed for use in laboratories, which detects the number
of CGG triplet repeats (cytosine-guanine-guanine) in the 5’ untranslated region of the gene for fragile X mental
retardation (“Fragile X mental retardation-1”: FMR1). It aims to aid diagnosis of the clinical disease associated
with Fragile X syndrome, for example, mental retardation, primary ovarian failure, and tremors / ataxia.
Adellgene Huntington Disease (HD) is an in vitro diagnostic kit designed for use in clinical laboratories. The kit detects the number of repetitions of the CAG (cytosine-adenine-guanine) triplet, located on exon 1 of the IT15 gene (HTT), which can result in the formation of Huntington’s disease, also called Huntington’s Chorea. It aims to aid the clinical diagnosis associated with Huntington’s chorea, such as: subtle changes in coordination, involuntary minor movements, difficulty mentally planning, and often a depressed or irritable mood.
Adellgene® Myotonic Dystrophy Screening is a kit designed for use in clinical laboratories which detects the
number of repetitions of CTG of 3´UTR region of the DMPK gene located in chromosome 19 resulting in Myotonic
Dystrophy disease. It aims to aid clinical diagnosis associated with clinical findings in myotonic dystrophy
type 1 (DM1) that span from mild to severe symptoms.