Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.).
Background/ FUNCTION.
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
IHC use Immunohistochemistry of paraffin-embedded mouse spleen tissue slide using PAab09945(NOS3 Antibody) at dilution of 1:100 WB use LO2 cells were subjected to SDS PAGE followed by western blot with PAab09945(NOS3 antibody) at dilution of 1:1000.
Protein Information.
Gene ID 4846.
Uniprot ID P29474.
Calculated MW 140kDa.
Research Area Signal Transduction, Metabolism, Cardiovascular, Developmental biology, Neuroscience, Stem Cells, Immunology.
Alternative Name ECNOS, eNOS, nitric oxide synthase 3.