MGMT antibody

In stock
SKU/Catalog Number
PAab10100

Catalog Number: PAab10100

  • Isotype IgG
  • Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
  • Background/ FUNCTION
  • Involved in the cellular defense against the biological effects of O6-methylguanine(O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  • Immunogen O-6-methylguanine-DNA methyltransferase
  • Specificity Human
  • Tested Application ELISA, IHC
  • Recommended dilution IHC: 1:50 - 1:500
  • IHC use
  • Immunohistochemistry of paraffin-embedded human liver cancer using PAab10100(MGMT antibody) at dilution of 1:200
  • WB use
  • Protein Information
  • Gene ID 4255
  • Uniprot ID P16455
  • Calculated MW 22 kDa
  • Research Area Cancer, Immunology, Metabolism
  • Alternative Name MGMT
More Information
Intended UsePurification Immunogen affinity purified , Purity 95% as determined by SDS-PAGE
Companybioactiva diagnostica GmbH
Storage condition2-8°C
Product NumberPAab10100
ManufacturerLife Science Market
CertificationFor research only
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