LOXL1 antibody
In stock
SKU/Catalog Number
PAab09975
Catalog Number: PAab09975
- Isotype IgG
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
- Background/ FUNCTION This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome.
- Immunogen lysyl oxidase-like 1
- Specificity Human, Mouse, Rat
- Tested Application ELISA, WB
- Recommended dilution WB: 1:500 - 1:2000
- IHC use
- WB use
- A549 cells were subjected to SDS PAGE followed by western blot with PAab09975(LOXL1 Antibody) at dilution of 1:1000
- Protein Information
- Gene ID 4016
- Uniprot ID Q08397
- Calculated MW 70kDa
- Research Area Cancer, Metabolism
- Alternative Name LOL, LOXL, LOXL1, Lysyl oxidase homolog 1, lysyl oxidase like 1, Lysyl oxidase like protein 1
| Intended Use | Purification Immunogen affinity purified , Purity 95% as determined by SDS-PAGE |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab09975 |
| Manufacturer | Life Science Market |
| Certification | For research only |
| Order | Request Quote |
