GAD1 antibody
In stock
SKU/Catalog Number
PAab09843
Catalog Number: PAab09843
- Isotype IgG
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
- Background/ FUNCTION
- This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
- Immunogen glutamate decarboxylase 1
- Specificity Human, Mouse, Rat
- Tested Application ELISA, WB
- Recommended dilution WB: 1:500 - 1:2000
- IHC use
- WB use
- Jurkat cells were subjected to SDS PAGE followed by western blot with PAab09843( GAD1 Antibody) at dilution of 1:1000
- Protein Information
- Gene ID 2571
- Uniprot ID Q99259
- Calculated MW 348 kDa
- Research Area Neuroscience, Stem Cells, Metabolism
- Alternative Name FLJ45882, GAD, GAD 67, GAD1, GAD67, Glutamate decarboxylase 1, SCP
| Intended Use | Purification Immunogen affinity purified , Purity 95% as determined by SDS-PAGE |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab09843 |
| Manufacturer | Life Science Market |
| Certification | For research only |
| Order | Request Quote |
