Endoglin/CD105 antibody

In stock
SKU/Catalog Number
PAab10035

Catalog Number: PAab10035

  • Isotype IgG
  • Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
  • Background/ FUNCTION
  • This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Immunogen endoglin
  • Specificity Human
  • Tested Application ELISA, WB
  • Recommended dilution WB: 1:200-1:2000
  • IHC use
  • WB use
  • MCF-7 cells were subjected to SDS PAGE followed by western blot with PAab10035(ENG antibody) at dilution of 1:1000
  • Protein Information
  • Gene ID 2022
  • Uniprot ID P17813
  • Calculated MW 50 kDa, 67 kDa
  • Research Area Signal Transduction, Cardiovascular, Immunology, Cancer, Developmental biology, Stem Cells
  • Alternative Name CD105, END, Endoglin, ENG, FLJ41744, HHT1, ORW, ORW1
More Information
Intended UsePurification Immunogen affinity purified, Purity 95% as determined by SDS-PAGE
Companybioactiva diagnostica GmbH
Storage condition2-8°C
Product NumberPAab10035
ManufacturerLife Science Market
CertificationFor research only
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