Collagen Type I antibody

In stock
SKU/Catalog Number
PAab09910

Catalog Number: PAab09910

  • Isotype IgG1
  • Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
  • Background/ FUNCTION
  • This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
  • Immunogen collagen, type I, alpha 2
  • Specificity Human
  • Tested Application ELISA, IHC
  • Recommended dilution IHC: 1:2000 - 1:8000
  • IHC use Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using PAab09910( COL1A2 Antibody) at dilution of 1:5000
  • WB use
  • Protein Information
  • Gene ID 1278
  • Uniprot ID P08123
  • Calculated MW
  • Research Area Stem Cells, Cardiovascular
  • Alternative Name Alpha 2 type I collagen, COL1A2, Collagen alpha 2(I) chain, Collagen Type I, collagen, type I, alpha 2, OI4
More Information
Intended UsePurification protein A+G purified, Purity 95% as determined by SDS-PAGE
Companybioactiva diagnostica GmbH
Storage condition2-8°C
Product NumberPAab09910
ManufacturerLife Science Market
CertificationFor research only
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