Cdc20 antibody
In stock
SKU/Catalog Number
PAab09997
Catalog Number: PAab09997
- Isotype IgG
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
- Background/ FUNCTION
- Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome(APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.
- Immunogen cell division cycle 20 homolog
- Specificity Human
- Tested Application ELISA, WB, IHC
- Recommended dilution WB: 1:500-1:2000; IHC: 1:20-1:200
- IHC use Immunohistochemistry of paraffin-embedded human colon cancer using PAab09997(CDC20 antibody) at dilution of 1:100
- WB use HeLa cells were subjected to SDS PAGE followed by western blot with PAab09997(CDC20 antibody) at dilution of 1:1000
- Protein Information
- Gene ID 991
- Uniprot ID Q12834
- Calculated MW 55 kDa
- Research Area Cell Division and Proliferation, Metabolism
- Alternative Name CDC20, CDC20A, p55CDC
| Intended Use | Purification Immunogen affinity purified, Purity 95% as determined by SDS-PAGE |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab09997 |
| Manufacturer | Life Science Market |
| Certification | For research only |
| Order | Request Quote |
