Cdc20 antibody

In stock
SKU/Catalog Number

Catalog Number: PAab09997

  • Isotype IgG
  • Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
  • Background/ FUNCTION
  • Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome(APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.
  • Immunogen cell division cycle 20 homolog
  • Specificity Human
  • Tested Application ELISA, WB, IHC
  • Recommended dilution WB: 1:500-1:2000; IHC: 1:20-1:200
  • IHC use Immunohistochemistry of paraffin-embedded human colon cancer using PAab09997(CDC20 antibody) at dilution of 1:100
  • WB use HeLa cells were subjected to SDS PAGE followed by western blot with PAab09997(CDC20 antibody) at dilution of 1:1000
  • Protein Information
  • Gene ID 991
  • Uniprot ID Q12834
  • Calculated MW 55 kDa
  • Research Area Cell Division and Proliferation, Metabolism
  • Alternative Name CDC20, CDC20A, p55CDC
More Information
Intended UsePurification Immunogen affinity purified, Purity 95% as determined by SDS-PAGE
Companybioactiva diagnostica GmbH
Storage condition2-8°C
Product NumberPAab09997
ManufacturerLife Science Market
CertificationFor research only
OrderRequest Quote