CD150 antibody(PE conjugated)

In stock
SKU/Catalog Number
PAab09790

Catalog Number: PAab09790

  • Isotype IgG1
  • Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
  • Background/ FUNCTION
  • CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signalinglymphocyte activation molecule) orIPO-3. CD150, asingle chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained onTh1 but notTh2 clones.Tregulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-g production byTh1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoieticstem cell studies.
  • Immunogen signaling lymphocytic activation molecule family member 1
  • Specificity Mouse
  • Tested Application FC
  • Recommended dilution 1
  • Alternative Name CDw150, Slamf1, Slam, ESTM51, IPO-3, 4933415F16, AA177906
More Information
Intended UsePurification Protein G purified, Purity 95% as determined by SDS-PAGE
Companybioactiva diagnostica GmbH
Storage condition2-8°C
Product NumberPAab09790
ManufacturerLife Science Market
CertificationFor research only
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