CD150 antibody(PE conjugated)
In stock
SKU/Catalog Number
PAab09790
Catalog Number: PAab09790
- Isotype IgG1
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
- Background/ FUNCTION
- CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signalinglymphocyte activation molecule) orIPO-3. CD150, asingle chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained onTh1 but notTh2 clones.Tregulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-g production byTh1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoieticstem cell studies.
- Immunogen signaling lymphocytic activation molecule family member 1
- Specificity Mouse
- Tested Application FC
- Recommended dilution 1
- Alternative Name CDw150, Slamf1, Slam, ESTM51, IPO-3, 4933415F16, AA177906
| Intended Use | Purification Protein G purified, Purity 95% as determined by SDS-PAGE |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab09790 |
| Manufacturer | Life Science Market |
| Certification | For research only |
| Order | Request Quote |
