CD14 antibody
In stock
SKU/Catalog Number
PAab10077
Catalog Number: PAab10077
- Isotype IgG
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
- Background/ FUNCTION
- Coreceptor for bacterial lipopolysaccharide(PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide(LPS)(PubMed:20133493, PubMed:23264655). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response(PubMed:8612135). Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway(PubMed:16880211).
- Immunogen CD14 molecule
- Specificity Human
- Tested Application ELISA, IHC
- Recommended dilution IHC: 1:20-1:200
- IHC use Immunohistochemistry of paraffin-embedded human kidney tissue slide using PAab10077(CD14 Antibody) at dilution of 1:200
- WB use
- Protein Information
- Gene ID 929
- Uniprot ID P08571
- Calculated MW 50-55 kDa
- Research Area Stem Cells, Immunology, Signal Transduction, Cancer
- Alternative Name CD14, CD14 molecule
| Intended Use | Purification Immunogen affinity purified, Purity 95% as determined by SDS-PAGE |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab10077 |
| Manufacturer | Life Science Market |
| Certification | For research only |
| Order | Request Quote |
