CASP14 antibody
In stock
SKU/Catalog Number
PAab09900
Catalog Number: PAab09900
- Isotype IgG
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
- Background/ FUNCTION
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.
- Immunogen CASP14
- Specificity Human, Mouse, Rat
- Tested Application ELISA, WB, IF
- Recommended dilution WB: 1:500 - 1:2000; IF: 1:50 - 1:200
- IHC use
- WB use
- 293T cells were subjected to SDS PAGE followed by western blot with PAab09900( CASP14 antibody) at dilution of 1:1000
- Protein Information
- Gene ID 23581
- Uniprot ID P31944
- Calculated MW 30 kDa
- Research Area Cell Division and Proliferation
- Alternative Name CASP14, ARCI12, caspase-14
| Intended Use | Alternative Name CASP14, ARCI12, caspase-14, Purification Immunogen affinity purified |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab09900 |
| Manufacturer | Life Science Market |
| Certification | For research only |
| Order | Request Quote |
