ARHGEF1 antibody
In stock
SKU/Catalog Number
PAab10091
Catalog Number: PAab10091
- Isotype IgG
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
- Background/ FUNCTION
- Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12(GNA12) and alpha-13(GNA13) subunits. Acts as GTPase-activating protein(GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor(GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.
- Immunogen Rho guanine nucleotide exchange factor(GEF) 1
- Specificity Human, Rat
- Tested Application ELISA, IHC
- Recommended dilution
- IHC: 1:20-1:200 IHC use Immunohistochemistry of paraffin-embedded rat lung using PAab10091(PER2 antibody) at dilution of 1:50
- WB use
- Protein Information
- Gene ID 9138
- Uniprot ID Q92888
- Calculated MW 102-110 kDa
- Research Area Signal Transduction, Metabolism
- Alternative Name ARHGEF1, GEF1, LBCL2, LSC, P115 RHOGEF, p115RhoGEF, SUB1.5, ARHG1
| Intended Use | Purification Immunogen affinity purified, Purity 95% as determined by SDS-PAGE |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab10091 |
| Manufacturer | Life Science Market |
| Certification | For research only |
| Order | Request Quote |
