Visfatin antibody

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SKU/Catalog Number
PAab09847

Katalognummer: PAab09847

  • Isotype IgG2b.
  • Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.).
  • Background/ FUNCTION.
  • Nicotinamide phosphoribosyltransferase(NAMPT) has two usual synonyms termed Visfatin and PBEF. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD, which is the rate limiting component in the mammalian NAD biosynthesis pathway. NAMPT is localized in cytoplasm and expressed in large amounts in bone marrow, liver tissue, and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. NAMPT levels are altered in plasma of patients with type 2 diabetes mellitus(T2DM), and it is now evidenced that NAMPT may plays a role in lipid metabolism.
  • Immunogen nicotinamide phosphoribosyltransferase.
  • Specificity Human, Mouse, Rat.
  • Tested Application ELISA, WB, IHC, IF.
  • Recommended dilution WB: 1:1000-1:4000; IHC: 1:50-1:500; IF: 1:50-1:500.
  • IHC use Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using PAab09847( Visfatin antibody ) at dilution of 1:200.
  • WB use.
  • rat heart tissue were subjected to SDS PAGE followed by western blot with PAab09847( Visfatin antibody ) at dilution of 1:2000.
  • Protein Information.
  • Gene ID 10135.
  • Uniprot ID P43490.
  • Calculated MW.
  • Research Area Neuroscience, Immunology, Signal Transduction, Metabolism, Cardiovascular.
  • Alternative Name 1110035O14Rik, DKFZp666B131, NAmPRTase, NAMPT, PBEF, PBEF1, Pre B cell enhancing factor, VF, VISFATIN.
Weitere Informationen
Intended UsePurification protein A+G purified , Purity 95% as determined by SDS-PAGE.
Companybioactiva diagnostica GmbH
Storage condition2-8°C
Product NumberPAab09847
HerstellerLife Science Market
ZertifizierungFor research only
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