PKC gamma antibody
Auf Lager
SKU/Catalog Number
PAab10007
Katalognummer: PAab10007
- Isotype IgG.
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.).
- Background/ FUNCTION.
- Protein kinase C(PKC) is a family of serine-and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC gamma is a neuron-specific member of the classical PKCs and is activated and translocated to subcellular regions as a result of various stimuli, including diacylglycerol synthesis, increased intracellular Ca(2+) and phorbol esters. Defects in this protein have been associated with spinocerebellar ataxia type 14(SCA14), an autosomal dominant neurodegenerative disease.
- Immunogen protein kinase C, gamma.
- Specificity Mouse, Rat.
- Tested Application ELISA, WB, IHC.
- Recommended dilution WB: 1:500-1:2000; IHC: 1:100-1:500.
- IHC use Immunohistochemistry of paraffin-embedded rat brain tissue slide using PAab10007(PRKCG Antibody) at dilution of 1:200.
- WB use.
- mouse brain tissue were subjected to SDS PAGE followed by western blot with PAab10007(PRKCG antibody) at dilution of 1:1000.
- Protein Information.
- Gene ID.
- Uniprot ID P63318.
- Calculated MW 78 kDa.
- Research Area Signal Transduction, Metabolism, Cardiovascular, Immunology, Neuroscience.
- Alternative Name PKC gamma, PKCC, PKCG, PRKCG, Protein kinase C gamma type, protein kinase C, gamma, SCA14.
| Intended Use | Purification Immunogen affinity purified , Purity 95% as determined by SDS-PAGE. |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab10007 |
| Hersteller | Life Science Market |
| Zertifizierung | For research only |
| Order | Request Quote |
