Phospho-VEGF Receptor 2-Y1175 antibody
Auf Lager
SKU/Catalog Number
PAab09964
Katalognummer: PAab09964
- Isotype IgG.
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.).
- Background/ FUNCTION.
- KDR, also named as VEGFR-2, FLK1 and CD309, is a receptor for VEGF or VEGFC. KDR which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas.
- Immunogen A phospho.
- specific peptide corresponding to residues surrounding Y1175 of human VEGF Receptor 2.
- Specificity Human, Mouse, Rat.
- Tested Application ELISA, WB, IHC Recommended dilution WB: 1:500 - 1:1000; IHC: 1:50 - 1:100.
- IHC use Immunohistochemistry of paraffin-embedded human breast carcinoma tissue slide using PAab09964 at dilution of 1:50.
- WB use.
- HUVE cells were subjected to SDS PAGE followed by western blot with PAab09964 at dilution of 1:600.
- Protein Information.
- Gene ID 3791.
- Uniprot ID P35968.
- Calculated MW 250 kDa.
- Research Area.
- Alternative Name CD309, Fetal liver kinase 1, FLK 1, FLK1, KDR, Kinase insert domain receptor, VEGF Receptor 2, VEGFR, VEGFR 2, VEGFR2.
| Intended Use | Purification Immunogen affinity purified , Purity 95% as determined by SDS-PAGE. |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab09964 |
| Hersteller | Life Science Market |
| Zertifizierung | For research only |
| Order | Request Quote |
