PARP1 antibody
Auf Lager
SKU/Catalog Number
PAab09939
Katalognummer: PAab09939
- Isotype IgG1.
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.).
- Background/ FUNCTION.
- PARP1 (poly(ADP-ribose) polymerase 1) is a nuclear enzyme catalyzing the poly(ADP-ribosyl)ation of many key proteins in vivo. The normal function of PARP1 is the routine repair of DNA damage. Activated by DNA strand breaks, the PARP1 is cleaved into an 85 to 89-kDa COOH-terminal fragment and a 24-kDa NH2-terminal peptide by caspases during the apoptotic process. The appearance of PARP fragments is commonly considered as an important biomarker of apoptosis.
- Immunogen poly (ADP-ribose) polymerase 1.
- Specificity Human, Mouse, Rat.
- Tested Application ELISA, WB, IHC, IF.
- Recommended dilution WB: 1:5000 - 1:30000; IHC: 1:100 - 1:1000; IF: 1:50 - 1:500.
- IHC use Immunohistochemistry of paraffin-embedded human breast cancer using PAab09939(PARP1 antibody) at dilution of 1:600.
- WB use.
- HeLa cells were subjected to SDS PAGE followed by western blot with PAab09939(PARP1 Antibody) at dilution of 1:20000.
- Protein Information.
- Gene ID 142.
- Uniprot ID P09874.
- Calculated MW 115 kDa, 89 kDa Research Area Metabolism.
- Alternative Name ADPRT, ADPRT 1, ADPRT1, pADPRT 1, PARP, PARP 1, PARP1, poly (ADP ribose) polymerase 1, Poly [ADP ribose] polymerase 1, Poly[ADP ribose] synthase 1, PPOL.
| Intended Use | Purification protein A+G purified , Purity 95% as determined by SDS-PAGE. |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab09939 |
| Hersteller | Life Science Market |
| Zertifizierung | For research only |
| Order | Request Quote |
