P62/SQSTM1 antibody
Auf Lager
SKU/Catalog Number
PAab09853
Katalognummer: PAab09853
- Isotype IgG2a.
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.).
- Background/ FUNCTION.
- This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
- Immunogen sequestosome 1.
- Specificity Human, Mouse.
- Tested Application ELISA, WB, IHC, IF.
- Recommended dilution WB: 1:1000 - 1:4000; IHC: 1:50 - 1:500; IF: 1:20 - 1:200.
- IHC use Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using PAab09853(SQSTM1 Antibody) at dilution of 1:100.
- WB use.
- HEK-293 cells were subjected to SDS PAGE followed by western blot with PAab09853(SQSTM1 antibody) at dilution of 1:2000.
- Protein Information.
- Gene ID 8878.
- Uniprot ID Q13501.
- Calculated MW 25 kDa.
- Research Area Neuroscience, Cardiovascular, Metabolism, Signal Transduction.
- Alternative Name P62, sequestosome 1, SQSTM1, Ubiquitin binding protein p62.
| Intended Use | Purification protein A+G purified , Purity 95% as determined by SDS-PAGE. |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab09853 |
| Hersteller | Life Science Market |
| Zertifizierung | For research only |
| Order | Request Quote |
