P Glycoprotein antibody
Auf Lager
SKU/Catalog Number
PAab09805
Katalognummer: PAab09805
- Isotype IgG.
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.).
- Background/ FUNCTION.
- ABCB1(also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer. .
- Immunogen ABCB1.
- Specificity Human, Mouse.
- Tested Application ELISA, WB, IP, IHC.
- Recommended dilution WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:50-1:500.
- IHC use Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using PAab09805(P glycoprotein antibody) at dilution of 1:500.
- WB use.
- HepG2 cells were subjected to SDS PAGE followed by western blot with PAab09805(P glycoprotein antibody) at dilution of 1:300.
- Protein Information.
- Gene ID.
- Uniprot ID P08183.
- Calculated MW 173 kDa.
- Research Area Neuroscience, Immunology, Metabolism.
- Alternative Name ABCB1, CD243, GP170, MDR1, Multidrug resistance protein 1, P glycoprotein 1.
| Intended Use | Purification Immunogen affinity purified , Purity 95% as determined by SDS-PAGE. |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab09805 |
| Hersteller | Life Science Market |
| Zertifizierung | For research only |
| Order | Request Quote |
