LAT antibody
Auf Lager
SKU/Catalog Number
PAab10030
Katalognummer: PAab10030
- Isotype IgG
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
- Background/ FUNCTION
- Required for TCR(T-cell antigen receptor)-and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3(low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1(high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
- Immunogen linker for activation of T cells
- Specificity Human
- Tested Application ELISA, WB
- Recommended dilution WB: 1:500 - 1:2000
- IHC use
- WB use
- Jurkat cells were subjected to SDS PAGE followed by western blot with PAab10030(LAT antibody) at dilution of 1:1000
- Protein Information
- Gene ID 27040
- Uniprot ID O43561
- Calculated MW 36-38 kDa
- Research Area Immunology, Signal Transduction
- Alternative Name LAT, LAT1, p36 38, pp36
| Intended Use | Purification Immunogen affinity purified , Purity 95% as determined by SDS-PAGE |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab10030 |
| Hersteller | Life Science Market |
| Zertifizierung | For research only |
| Order | Request Quote |
