HLA-G antibody
Auf Lager
SKU/Catalog Number
PAab09952
Katalognummer: PAab09952
- Isotype IgG1
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
- Background/ FUNCTION
- Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface, where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance.
- Immunogen MHC class I antigen G
- Specificity Human
- Tested Application ELISA, WB, IHC
- Recommended dilution WB: 1:2000-1:10000; IHC: 1:50-1:200
- IHC use Immunohistochemistry of paraffin-embedded human placenta tissue slide using PAab09952( HLA-G Antibody) at dilution of 1:200
- WB use
- human placenta tissue were subjected to SDS PAGE followed by western blot with PAab09952( HLA-G Antibody) at dilution of 1:5000
- Protein Information
- Gene ID 3135
- Uniprot ID P17693
- Calculated MW 38 kDa
- Research Area Immunology
- Alternative Name HLA 6.0, HLA G, HLA G antigen, HLAG, HLA-G, MHC class I antigen G, MHC G
| Intended Use | Purification protein A+G purified , Purity 95% as determined by SDS-PAGE |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab09952 |
| Hersteller | Life Science Market |
| Zertifizierung | For research only |
| Order | Request Quote |
