HDAC4 antibody
Auf Lager
SKU/Catalog Number
PAab09984
Katalognummer: PAab09984
- Isotype IgG
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
- Background/ FUNCTION
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
- Immunogen histone deacetylase 4
- Specificity Human, Mouse
- Tested Application ELISA, WB
- Recommended dilution WB: 1:500 - 1:2000
- IHC use
- WB use
- HeLa cells were subjected to SDS PAGE followed by western blot with PAab09984(HDAC4 antibody) at dilution of 1:1000
- Protein Information
- Gene ID 9759
- Uniprot ID P56524
- Calculated MW 130 kDa
- Research Area Epigenetics, Cardiovascular, Metabolism, Developmental biology
- Alternative Name KIAA0288
| Intended Use | Purification Immunogen affinity purified , Purity 95% as determined by SDS-PAGE |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab09984 |
