Cytochrome c antibody
Auf Lager
SKU/Catalog Number
PAab098271
Katalognummer: PAab098271
- Isotype IgG2a
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
- Background/ FUNCTION
- Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.
- Immunogen Cytochrome c
- Specificity Human, Mouse, Rat
- Tested Application ELISA, WB, IHC
- Recommended dilution WB: 1:5000-1:30000; IHC: 1:100-1:1000
- IHC use Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using PAab098271( Cytochrome c Antibody) at dilution of 1:600
- WB use
- Hela cells were subjected to SDS PAGE followed by western blot with PAab098271(Cytochrome c antibody) at dilution of 1:20000
- Protein Information
- Gene ID 54205
- Uniprot ID P99999
- Calculated MW 150 kDa
- Research Area Cardiovascular, Metabolism
- Alternative Name CYC, CYCS, Cytochrome c, cytochrome c, somatic, HCS, THC4
| Intended Use | Purification Protein A+G purification, Purity 95% as determined by SDS-PAGE |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab098271 |
| Hersteller | Life Science Market |
| Zertifizierung | For research only |
| Order | Request Quote |
