CTSC antibody
Auf Lager
SKU/Catalog Number
PAab09934
Katalognummer: PAab09934
- Isotype IgG
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
- Background/ FUNCTION
- This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.
- Immunogen Cathepsin C
- Specificity Human, Mouse, Rat
- Tested Application ELISA, WB, IHC
- Recommended dilution WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
- IHC use Immunohistochemistry of paraffin-embedded rat kidney tissue slide using PAab09934 (CTSC antibody) at dilution of 1:100
- WB use
- Hela cells were subjected to SDS PAGE followed by western blot with PAab09934 (CTSC antibody) at dilution of 1:1000
- Protein Information
- Gene ID 1075
- Uniprot ID P53634
- Calculated MW 70 kDa Research Area Cell Division and Proliferation
- Alternative Name CPPI, DPP-I, DPP1, DPPI, HMS, JP, JPD, PALS, PDON1, PLS
| Intended Use | Purification Immunogen affinity purified, Purity 95% as determined by SDS-PAGE |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab09934 |
| Hersteller | Life Science Market |
| Zertifizierung | For research only |
| Order | Request Quote |
