CD3 epsilon monoclonal antibody
Auf Lager
SKU/Catalog Number
PAab09892
Katalognummer: PAab09892
- Isotype IgG
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
- Background/ FUNCTION
- CD3 is a complex of proteins that directly associates with the T cell receptor (TCR). The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells. This anti-CD3 is a monoclonal antibody directed against the epsilon chain of human CD3 molecule.
- Immunogen CD3e molecule, epsilon (CD3-TCR complex)
- Specificity Human
- Tested Application ELISA, WB, IHC
- Recommended dilution WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
- IHC use Immunohistochemistry of paraffin-embedded human spleen tissue slide using PAab09892( CD3E Antibody) at dilution of 1:100
- WB use
- Jurkat cells were subjected to SDS PAGE followed by western blot with PAab09892( CD3E Antibody) at dilution of 1:1000
- Protein Information
- Gene ID 916
- Uniprot ID P07766
- Calculated MW 85 kDa
- Research Area Cancer, Immunology, Signal Transduction
- Alternative Name CD3, CD3 epsilon, CD3E, CD3-epsilon, T3E, TCRE
| Intended Use | Purification Protein A+G purification, Purity 95% as determined by SDS-PAGE |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab09892 |
| Hersteller | Life Science Market |
| Zertifizierung | For research only |
| Order | Request Quote |
