CD206 antibody

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SKU/Catalog Number
PAab09912

Katalognummer: PAab09912

  • Isotype IgG
  • Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
  • Background/ FUNCTION
  • CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane protein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains(responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail. It is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia.
  • Immunogen mannose receptor, C type 1
  • Specificity Human, Mouse, Rat
  • Tested Application ELISA, WB, IHC, IF
  • Recommended dilution WB: 1:200-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200
  • IHC use Immunohistochemistry of paraffin-embedded human lung using PAab09912(CD206 antibody) at dilution of 1:100
  • WB use
  • Mouse liver were subjected to SDS PAGE followed by western blot with PAab09912(CD206 antibody) at dilution of 1:1000
  • Protein Information
  • Gene ID 4360
  • Uniprot ID P22897
  • Calculated MW 166 kDa
  • Research Area Neuroscience, Immunology
  • Alternative Name CD206, CLEC13D, Macrophage mannose receptor 1, Mannose receptor, mannose receptor, C type 1, MMR, MRC1
Weitere Informationen
Intended UsePurification Immunogen affinity purified, Purity 95% as determined by SDS-PAGE
Companybioactiva diagnostica GmbH
Storage condition2-8°C
Product NumberPAab09912
HerstellerLife Science Market
ZertifizierungFor research only
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