CD206 antibody
Auf Lager
SKU/Catalog Number
PAab09912
Katalognummer: PAab09912
- Isotype IgG
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
- Background/ FUNCTION
- CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane protein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains(responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail. It is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia.
- Immunogen mannose receptor, C type 1
- Specificity Human, Mouse, Rat
- Tested Application ELISA, WB, IHC, IF
- Recommended dilution WB: 1:200-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200
- IHC use Immunohistochemistry of paraffin-embedded human lung using PAab09912(CD206 antibody) at dilution of 1:100
- WB use
- Mouse liver were subjected to SDS PAGE followed by western blot with PAab09912(CD206 antibody) at dilution of 1:1000
- Protein Information
- Gene ID 4360
- Uniprot ID P22897
- Calculated MW 166 kDa
- Research Area Neuroscience, Immunology
- Alternative Name CD206, CLEC13D, Macrophage mannose receptor 1, Mannose receptor, mannose receptor, C type 1, MMR, MRC1
| Intended Use | Purification Immunogen affinity purified, Purity 95% as determined by SDS-PAGE |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab09912 |
| Hersteller | Life Science Market |
| Zertifizierung | For research only |
| Order | Request Quote |
