CD14 antibody

Auf Lager
SKU/Catalog Number
PAab10077

Katalognummer: PAab10077

  • Isotype IgG
  • Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
  • Background/ FUNCTION
  • Coreceptor for bacterial lipopolysaccharide(PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide(LPS)(PubMed:20133493, PubMed:23264655). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response(PubMed:8612135). Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway(PubMed:16880211).
  • Immunogen CD14 molecule
  • Specificity Human
  • Tested Application ELISA, IHC
  • Recommended dilution IHC: 1:20-1:200
  • IHC use Immunohistochemistry of paraffin-embedded human kidney tissue slide using PAab10077(CD14 Antibody) at dilution of 1:200
  • WB use
  • Protein Information
  • Gene ID 929
  • Uniprot ID P08571
  • Calculated MW 50-55 kDa
  • Research Area Stem Cells, Immunology, Signal Transduction, Cancer
  • Alternative Name CD14, CD14 molecule
Weitere Informationen
Intended UsePurification Immunogen affinity purified, Purity 95% as determined by SDS-PAGE
Companybioactiva diagnostica GmbH
Storage condition2-8°C
Product NumberPAab10077
HerstellerLife Science Market
ZertifizierungFor research only
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