ARHGEF1 antibody

Name: ARHGEF1 antibody
Brand: bioactiva diagnostica GmbH
SKU: PAab10091

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SKU/Catalog Number

PAab10091

Katalognummer: PAab10091

Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12(GNA12) and alpha-13(GNA13) subunits. Acts as GTPase-activating protein(GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor(GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.
Immunogen Rho guanine nucleotide exchange factor(GEF) 1
Specificity Human, Rat
Tested Application ELISA, IHC
Recommended dilution
IHC: 1:20-1:200 IHC use Immunohistochemistry of paraffin-embedded rat lung using PAab10091(PER2 antibody) at dilution of 1:50
WB use
Protein Information
Gene ID 9138
Uniprot ID Q92888
Calculated MW 102-110 kDa
Research Area Signal Transduction, Metabolism
Alternative Name ARHGEF1, GEF1, LBCL2, LSC, P115 RHOGEF, p115RhoGEF, SUB1.5, ARHG1

Weitere Informationen
Intended Use	Purification Immunogen affinity purified, Purity 95% as determined by SDS-PAGE
Company	bioactiva diagnostica GmbH
Storage condition	2-8°C
Product Number	PAab10091
Hersteller	Life Science Market
Zertifizierung	For research only
Order	Request Quote