ARHGEF1 antibody

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SKU/Catalog Number

Katalognummer: PAab10091

  • Isotype IgG
  • Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
  • Background/ FUNCTION
  • Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12(GNA12) and alpha-13(GNA13) subunits. Acts as GTPase-activating protein(GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor(GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.
  • Immunogen Rho guanine nucleotide exchange factor(GEF) 1
  • Specificity Human, Rat
  • Tested Application ELISA, IHC
  • Recommended dilution
  • IHC: 1:20-1:200 IHC use Immunohistochemistry of paraffin-embedded rat lung using PAab10091(PER2 antibody) at dilution of 1:50
  • WB use
  • Protein Information
  • Gene ID 9138
  • Uniprot ID Q92888
  • Calculated MW 102-110 kDa
  • Research Area Signal Transduction, Metabolism
  • Alternative Name ARHGEF1, GEF1, LBCL2, LSC, P115 RHOGEF, p115RhoGEF, SUB1.5, ARHG1
Weitere Informationen
Intended UsePurification Immunogen affinity purified, Purity 95% as determined by SDS-PAGE
Companybioactiva diagnostica GmbH
Storage condition2-8°C
Product NumberPAab10091
HerstellerLife Science Market
ZertifizierungFor research only
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