Anti-Tyrosinase antibody

Host Rabbit ,Isotype IgG ,Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) ,Background/ FUNCTION ,The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene. ,Immunogen Tyrosinase ,Specificity Human, Mouse, Rat ,Tested Application ELISA, WB, IHC, IF ,Recommended dilution WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200 ,IHC use Immunohistochemistry of paraffin-embedded rat heart using PAab09856(TYR antibody) at dilution of 1:100 ,WB use ,mouse liver were subjected to SDS PAGE followed by western blot with PAab09856(TYR antibody) at dilution of 1:1000 ,Protein Information ,Gene ID 7299 ,Uniprot ID P14679 ,Calculated MW 126 kDa ,Research Area Signal Transduction, Metabolism, Cancer