alpha-synuclein antibody

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SKU/Catalog Number

Katalognummer: PAab09891

  • Isotype IgG1.
  •  Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.).
  • Background/ FUNCTION.
  • Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
  • Immunogen synuclein, alpha (non A4 component of amyloid precursor).
  • Specificity Human, Mouse, Rat.
  • Tested Application ELISA, IHC, WB.
  • Recommended dilution WB: 1:500 - 1:2000; IHC: 1:500 - 1:2000.
  • IHC use Immunohistochemistry of paraffin-embedded mouse brain using PAab09891(SNCA antibody) at dilution of 1:1000.
  • WB use.
  • mouse brain tissue were subjected to SDS PAGE followed by western blot with PAab09891(SNCA antibody) at dilution of 1:1000.
  • Protein Information.
  • Gene ID 6622.
  • Uniprot ID P37840.
  • Calculated MW 23 kDa.
  • Research Area Neuroscience Alternative Name Alpha synuclein, NACP, PARK1, PARK4, SNCA.
Weitere Informationen
Intended UsePurification protein A+G purified, Purity 95% as determined by SDS-PAGE
Companybioactiva diagnostica GmbH
Storage condition2-8°C
Product NumberPAab09891
HerstellerLife Science Market
ZertifizierungFor research only
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