Caspase 1 antibody
In stock
SKU/Catalog Number
PAab10015
Catalog Number: PAab10015
- Isotype IgG
- Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
- Background/ FUNCTION
- CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta(IL1B), IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products(PMID:21804020). It has 5 isoforms produced by alternative splicing.
- Immunogen caspase 1
- Specificity Human, Mouse
- Tested Application ELISA, WB, IHC
- Recommended dilution WB: 1:200-1:2000; IHC: 1:50-1:500
- IHC use Immunohistochemistry of paraffin-embedded human stomach tissue slide using PAab10015(CASP1 Antibody) at dilution of 1:100
- WB use
- NIH/3T3 cells were subjected to SDS PAGE followed by western blot with PAab10015(CASP1 antibody) at dilution of 1:1000
- Protein Information
- Gene ID 834
- Uniprot ID P29466
- Calculated MW 45-47 kDa, 30 kDa, 35 kDa
- Research Area Signal Transduction, Metabolism, Cardiovascular, Neuroscience
| Intended Use | Purification Immunogen affinity purified, Purity 95% as determined by SDS-PAGE |
|---|---|
| Company | bioactiva diagnostica GmbH |
| Storage condition | 2-8°C |
| Product Number | PAab10015 |
| Manufacturer | Life Science Market |
| Certification | For research only |
| Order | Request Quote |
